Sour Cream Chicken Enchilada Casserole

Looking for a creamy, comforting, and incredibly easy dinner recipe? This Sour Cream Chicken Enchilada Casserole is a family favorite that’s sure to satisfy even the pickiest eaters. Loaded with tender shredded chicken, layers of soft tortillas, tangy sour cream, green chilies, and melted cheese, this casserole brings all the flavors of traditional enchiladas—without the hassle of rolling each one individually.

Whether you’re prepping dinner for a busy weeknight or planning a make-ahead meal for a crowd, this easy casserole will become a go-to in your kitchen. Let’s dive into the details!


Why You’ll Love This Sour Cream Chicken Enchilada Recipe

  • Easy to prepare – No rolling required; just layer and bake.

  • Make-ahead friendly – Assemble in advance and refrigerate or freeze.

  • Family-approved – Creamy, cheesy, and full of flavor.

  • Perfect for potlucks or leftovers – Reheats beautifully.


Ingredients

Here’s what you’ll need:

  • 3 cups cooked shredded chicken (rotisserie chicken works great)

  • 2 cups sour cream

  • 1 can (10.5 oz) cream of chicken soup

  • 1 can (4 oz) diced green chilies

  • 1 ½ cups shredded Monterey Jack or Mexican blend cheese

  • 10 small flour tortillas (or 6 large)

  • 1 teaspoon garlic powder

  • ½ teaspoon onion powder

  • Salt and pepper, to taste

  • Optional garnish: chopped cilantro, green onions, jalapeños


Instructions: Sour Cream Chicken Enchilada

1. Preheat and Prep

Preheat your oven to 350°F (175°C). Lightly grease a 9×13-inch casserole dish.

2. Mix the Creamy Sauce

In a large bowl, combine the sour cream, cream of chicken soup, green chilies, garlic powder, onion powder, salt, and pepper. Mix well until smooth and creamy.

3. Layer the Casserole

Place a layer of torn tortillas (or cut into strips) in the bottom of the baking dish. Add half the shredded chicken and spoon one-third of the sauce on top. Sprinkle with a layer of cheese.

Repeat the layers: tortillas, chicken, sauce, and cheese. Finish with a final layer of tortillas, sauce, and the remaining cheese.

4. Bake

Cover with foil and bake for 25 minutes. Remove foil and bake an additional 10 minutes, or until the cheese is bubbly and slightly golden.

5. Let It Rest & Serve

Let the casserole sit for 5–10 minutes before serving. Garnish with cilantro or green onions if desired.


Tips for Success: Sour Cream Chicken Enchilada

  • Use rotisserie chicken to cut down on prep time.

  • Add spice by mixing in diced jalapeños or a dash of hot sauce into the sauce.

  • Make it ahead by assembling the casserole a day in advance and refrigerating. Just add 10 minutes to the baking time if baking from cold.


Serving Suggestions

Serve this rich and creamy casserole with a side of:

  • Mexican rice

  • Black beans or refried beans

  • A crisp green salad with lime vinaigrette

  • Chips and salsa or guacamole


Storage and Reheating

Refrigerator: Store leftovers in an airtight container for up to 4 days.
Freezer: Wrap the unbaked casserole tightly and freeze for up to 3 months.
Reheating: Bake at 350°F until warmed through, or microwave individual portions for 1–2 minutes.

Easy White Chicken Enchiladas Recipe

FAQs : Sour Cream Chicken Enchilada

Can I use corn tortillas instead of flour tortillas?

Yes! Corn tortillas offer a more traditional enchilada flavor and hold up well in casseroles. Just be sure to soften them slightly first to prevent cracking.


What kind of cheese works best?

Monterey Jack, Pepper Jack, or a Mexican blend all melt beautifully and complement the mild flavors of the casserole. Feel free to mix in cheddar for a sharper taste.


Can I make this casserole vegetarian?

Absolutely! Substitute the chicken with sautéed mushrooms, black beans, or even roasted vegetables like zucchini or bell peppers.


How spicy is this recipe?

This recipe is mild as written. If you prefer more heat, add diced jalapeños, chili powder, or use spicy green chilies.


Can I double the recipe?

Yes, this casserole scales well. Use two 9×13-inch pans or a larger baking dish if you’re feeding a crowd.


This Sour Cream Chicken Enchilada Casserole is everything you want in a weeknight dinner—easy, satisfying, and incredibly delicious. Once you try it, it’ll earn a permanent spot in your comfort food rotation.

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